Twitch Wild Rift Build with Highest Winrate - Guide Runes, Items, and Skill Order

Author: Son Acton

Twitch Wild Rift: is an ADC whose damage resonates with attack speed. Build items, runes and instructions for playing Twitch Wild Rift effectively.

Twitch Wild Rift

Twitch Wild Rift

Patch 5.0c

Marksman Marksman - Easy - Position: bot

Damage: Magic

Power Spike







Tier D
Win rate 47.86%
Pick rate 3.4%
Ban rate 1.1%
Twitch Wild Rift Build
Twitch: Wild Rift Build Guide

Twitch's Item Build & Runes

Twitch runes Win 45.23% and Pick 32.31%

Twitch runes Mid with Win 53.92% and Pick 24.45%

First Strike


Coup de Grace

Legend: Alacrity

Sudden Impact

Build Twitch Wild Rift with the highest win rate

  • Item Boots of Mana Boots of Mana
  • Item Runaan's Hurricane Runaan's Hurricane
  • Item Nashor's Tooth Nashor's Tooth
  • Item Liandry's Torment Liandry's Torment
  • Item Rabadon's Deathcap Rabadon's Deathcap
  • Item Crown of the Shattered Queen Crown of the Shattered Queen

Twitch Wild Rift build second

  • Item  Boots of Mana Boots of Mana
  • Item  Nashor's Tooth Nashor's Tooth
  • Item  Runaan's Hurricane Runaan's Hurricane
  • Item  Liandry's Torment Liandry's Torment
  • Item  Rabadon's Deathcap Rabadon's Deathcap
  • Item  Morellonomicon Morellonomicon

See more build Zoe Wild Rift in Meta

Twitch's Runes

Patch 5.0b has mages feeling mighty, and guess what? Our sneaky friend Twitch can tap into that power!  The "First Strike" rune is a no-brainer if you're building AP, turning him into a shadowy assassin, bursting onto unsuspecting lanes.

But maybe you crave that classic Twitch playstyle?  The "Conqueror" rune is your best bet for an AD build.  Poke and prod with those poison darts, stacking the Conqueror buff, then unleash a hail of toxic bullets with "Spray and Pray" – an absolute team fight nightmare!

Twitch position


Twitch's summoner spells

Flash + Thiêu đốt

Twitch Build Breakdown

Twitch's passive is a ticking time bomb – the more poison stacks you build, the faster he attacks! That's why we hunger for items that boost his attack speed, letting him unleash a storm of poisoned bolts.  For an AD build, "Runaan's Palace" isn't a luxury, it's a necessity.  Combine its power with his ultimate, and Twitch transforms into a whirlwind of destruction, capable of shredding entire enemy teams.

But there's a sneaky alternative – an AP build.  Instead of raw power, this focuses on stacking damage over time.  The beauty of magic items?  Fast cooldowns and potent true damage, perfect for melting even the toughest tanks. Plus, AP plays wickedly well with Twitch's 3rd skill. It becomes his venomous trump card! Of course, an AP build sacrifices some raw attack power, relying more on that insidious passive burn to finish the job.

Twitch ability

Twitch's skill order

Twitch's skill order

Twitch's abilities

Deadly Venom Deadly Venom

This isn't just poison, it's a slow, agonizing burn. Each bite injects a dose of potent venom that does true damage over time – that means no armor can stop it. Get those stacks up to five, and not only will your target be melting away, but you'll be attacking like a caffeinated hummingbird. Runaan's Hurricane? Think more like a venom-tipped machine gun.

Ambush Ambush

Fade into the shadows, get that adrenaline pumping, and then burst out swinging! This ability gives you camouflage and a speed boost, plus a bonus venom stack when you break cover.  And if you manage to take down a poisoned enemy, Ambush resets... it's time for another victim.

Venom Cask Venom Cask

Imagine a gooey, toxic grenade. Lob this cask into the fray and watch enemies get bogged down with a nasty slow,  while also getting coated in venom. The best part?  The faster you're attacking, the quicker you can chuck another one.

Contaminate Contaminate

Got a target stacked with five doses of venom? Time to unleash Contaminate for a burst of pain that'll make them regret picking a fight with you.  If they're unlucky enough to have buddies nearby, the poison might just spread and the whole fight becomes your personal highlight reel. Oh, and did I mention it tears through monsters? Jungle camps won't know what hit them.

Spray and Pray Spray and Pray

This is your "go big or go home" moment.  Spray and Pray turns you into a long-range turret, spewing out bolts of pain that shred through anything they touch.  Just watch your positioning – you're a sitting duck while this is active.

How to play Twitch

Save your ultimate when facing multiple opponents at the same time. To take full advantage of the damage from this move. Because the ultimate move can shoot through targets. Enemy teams standing next to each other will receive massive damage.

The early game is quite weak no matter which direction you build. Play safe. Twitch is an extremely strong champion in late game.

Ambush It is an effective tool for scouting and placing wards.

Contaminate Used to control an area. If you see the enemy is close together, throw "Infection" to slow down many champions at the same time.

A small note is that the longer Twitch trades dame, the more damage it causes.


Ambush + Contaminate

This is a perfect combo that increases attack speed very quickly. If you have a red buff available, it's easy to get an early kill.


Ambush Venom Cask Contaminate Spray and Pray

Twitch pros and cons


Damage explodes when approaching late game


Being CC means being controlled and it is very easy to be destroyed.

If you lack important skills. The only thing Twitch can do is stand from afar in combat.

Twitch counters

Use purple wards to avoid being suddenly ganked by Twitch

Game PlayGame play.

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